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應(yīng)用的篩選條件
本應(yīng)用簡(jiǎn)報(bào)為使用 XF 線粒體毒性檢測(cè)進(jìn)行化合物篩選和劑量響應(yīng)實(shí)驗(yàn)以及使用線粒 體毒性指標(biāo) (MTI) 解析結(jié)果數(shù)據(jù)提供了概念驗(yàn)證和示例。
| 英語(yǔ) (美國(guó)) | 完整版（PDF） |
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了解用于評(píng)估線粒體毒性的安捷倫 Seahorse XF 線粒體毒性測(cè)定解決方案的原理和參數(shù)計(jì)算
| 英語(yǔ) (美國(guó)) | 完整版（PDF） |
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A demonstration of combining microelectrode-based iPS cardiomyocyte contractility measurements with microplate-based bioenergetics assessment to characterize cellular responses to drug treatment.
Two Workflows: A Streamlined 384-well workflow to detect direct drug-induced mitochondrial dysfunction and Multiplexed workflow to detect mitochondrial toxicity after longer treatments
A demonstration of the performance of the Agilent MitoXpress Xtra oxygen consumption assay for identifying drug induced mitocondrial toxicity.
Multiplexed Screening of Drug-Induced Mitochondrial Dysfunction and Cytotoxicity
Screening for Drug-Induced Mitochondrial Dysfunction Using MitoXpress Xtra on Isolated Mitochondria
Poster - Cell-based Screening of Drug-Induced Metabolic Dysfunction
This poster Demonstrates the utility of Agilent Seahorse XF Real-Time ATP Rate Assay Kit and PMP in testing compound tox and understanding mechanism.