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使用高分辨率 LC/MS 對兩種利妥昔單抗生物仿制藥的完整質(zhì)量數(shù)、亞基質(zhì)量數(shù)和游離多聚糖進行比較研究
生物仿制藥的開發(fā)和生產(chǎn)需要與創(chuàng)新生物治療產(chǎn)品進行可比性研究。
生物仿制藥的開發(fā)和生產(chǎn)需要與創(chuàng)新生物治療產(chǎn)品進行可比性研究。
| 日語 (日本) | 完整版（PDF） |
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本應用摘要針對序列圖譜分析提供了一套完整的高通量工作流程解決方案。
| 日語 (日本) | 完整版（PDF） |
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本文詳細的介紹了蛋白（肽段）定量的意義及出現(xiàn) MRM 質(zhì)譜技術(shù)平臺的緣由、MRM 肽段定量的基本原理、安捷倫 MRM 肽段定量的完整定義以及安捷倫 LC/QQQ 肽段定量應用實例等。
LC/MS based characterization workflow of the GLP-1 therapeutic peptide liraglutide and its impurities using the 1290 Infinity II LC and 6545XT AdvanceBio LC/Q-TOF.
In the current study, We present a solid method for peptide quantification using capillary LC-MS/MS, emphasizing three key analytical parameters: (1) limit of detection (LOD) and limit of quantification (LOQ), (2) linear range for multiple peptides,...
This application note utilizes the 1260 Infinity II Bio Prime LC and InfinityLab LC/MSD iQ for the confirmation of GLP-1 (Liraglutide) sample.
An automated workflow for the analysis of protein phosphorylation from sample preparation with phosphopeptide enrichment to analysis by IMS.
Presents a method for peptide mapping using an Agilent LC/MSD XT and 1290 Infinity II LC.
Describes the identification and quantitation of chemically-modified recombinant mABs with the Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunt...