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This poster reveals to optimize T-cell differentiation in bioreactors using integrated Agilent cell analytics and feedback control to enhance CAR T-cell therapyproduction.
AACR 2025 poster: Chronic anti-CD3/CD28 stimulation during cell expansion generates exhausted T cells with a distinct metabolic and cytotoxic phenotype
This editorial showcases Agilent solutions for metabolic modulation enhancing CAR T-cell activation, persistence, and serial killing for improved cancer immunotherapy
Targeting the immune system has dramatically increased the need for tracking the native, and more recently, engineered phenotypes of multiple cell lineages.
The Agilent NovoCyte Flow Cytometer has become the backbone of the Department of Clinical Immunology lab at Aarhus University Hospital due its ease-of-use and stability.
A 16-color T cell immunophenotyping panel was developed for the Agilent NovoCyte Advanteon
to simultaneously analyze T cell differentiation, activation, exhaustion, and functional output through degranulation and cytokine expression
Examines the phosphorylation of signal transducer and activator of transcription (STAT) proteins in response to cytokine stimulation using a phosphoflow technique.