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應(yīng)用的篩選條件
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本應(yīng)用簡報為使用 XF 線粒體毒性檢測進行化合物篩選和劑量響應(yīng)實驗以及使用線粒 體毒性指標(biāo) (MTI) 解析結(jié)果數(shù)據(jù)提供了概念驗證和示例。
| 英語 (美國) | 完整版（PDF） |
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Research highlight confirming the critical role of metabolic fitness in CAR-NK cells and its importance to achieve superior clinical outcomes in immunotherapy.
This application note introduces a workflow that uses the XF Real-Time ATP rate assay data for identifying metabolic modulator and drug targets.
Supplemental procedures to perform XF assays in hypoxia chambers using the Agilent Seahorse XF Analyzer.