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多肽是由多個(gè)氨基酸通過(guò)酰胺鍵相連形成的化合物，可通過(guò)基因重組表達(dá)和化學(xué)合成等方法制備。多肽藥物生產(chǎn)過(guò)程中的肽相關(guān)雜質(zhì)是反映多肽化學(xué)純度的重要指示。由于其與目標(biāo)分子結(jié)構(gòu)有關(guān)或相似，質(zhì)量分析中具有一定的挑戰(zhàn)性。本次講座將針對(duì)多肽分析背景、多種正交分析技術(shù)展開肽相關(guān)雜質(zhì)的表征。