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Reversed-phase LC primary structure characterization workflow using Agilent AdvanceBio RP-mAb columns and Agilent 1260 Infinity Bio-Inert LC system
This Application Note shows the workflow solution for the physicochemical and biological characterization of a biosimilar and innovator rituximab.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| 文件出版號 | 5991-4266EN | ||
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles. mAb-glyco chip analysis built a glycan accurate mass database.
| 文件出版號 | 5990-2323EN | ||||
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
| 文件出版號 | 5991-2116EN | |||
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